产品名称
FLRT1 Rabbit Polyclonal Antibody
基因名称
FLRT1 UNQ752/PRO1483
蛋白名称
Leucine-rich repeat transmembrane protein FLRT1 (Fibronectin-like domain-containing leucine-rich transmembrane protein 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NZU1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NZU1/entry
免疫原
Synthesized peptide derived from part region of human protein
特异性
FLRT1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
fibronectin leucine rich transmembrane protein 1(FLRT1) Homo sapiens This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain. [provided by RefSeq, Jul 2008],
组织表达
Expressed in kidney and brain.
细胞定位
Cell membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane . Cytoplasmic vesicle membrane . Cytoplasm, perinuclear region . Cell junction, focal adhesion . Secreted . Cell projection, neuron projection . Cell junction . In addition to its location at the cell membrane, colocalizes with FGFR1 in punctate perinuclear cytoplasmic vesicles. Detected along neurites and at contacts between neurite termini and other cells. Proteolytic cleavage gives rise to a shedded ectodomain. .
功能
function:May have a function in cell adhesion and/or receptor signaling.,PTM:N-glycosylated.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 10 LRR (leucine-rich) repeats.,tissue specificity:Expressed in kidney and brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
