产品名称
KREM1 Rabbit Polyclonal Antibody
蛋白名称
Kremen protein 1 (Dickkopf receptor) (Kringle domain-containing transmembrane protein 1) (Kringle-containing protein marking the eye and the nose)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q96MU8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96MU8/entry
Mouse Swissprot No.
Q99N43
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q99N43
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q924S4
免疫原
Synthesized peptide derived from part region of human protein
特异性
KREM1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Single-pass type I membrane protein .
功能
function:Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling.,similarity:Contains 1 CUB domain.,similarity:Contains 1 kringle domain.,similarity:Contains 1 WSC domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
