BD-PN2115

PROX1 Rabbit Polyclonal Antibody

常规抗体

PROX1

Prospero homeobox protein 1 (Homeobox prospero-like protein PROX1) (PROX-1)

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

5629

Q92786

https://www.uniprot.org/uniprotkb/Q92786/entry

P48437

http://www.uniprot.org/uniprot/P48437

Synthesized peptide derived from part region of human protein

PROX1 Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000 ELISA 1:5000-20000

81kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012],

Most actively expressed in the developing lens. Detected also in embryonic brain, lung, liver and kidney. In adult, it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas.

Nucleus . RORG promotes its nuclear localization. .

function:May play a fundamental role in early development of CNS. May regulate gene expression and development of postmitotic undifferentiated young neurons.,similarity:Belongs to the Prospero homeobox family.,similarity:Contains 1 Prospero-type homeobox DNA-binding domain.,tissue specificity:Most actively expressed in the developing lens. Detected also in embryonic brain, lung, liver and kidney. In adult, it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.