BD-PE3195

SILV (Melanoma gp100) (3I5) Mouse Monoclonal antibody

常规抗体

PMEL

WB

Human

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Human recombinant protein fragment corresponding to amino acids 25-467 of human SILV (NP_008859)produced in SF9 cell.

WB 1:2000

-20°C/1 year

Mouse

IgG1

This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)