产品名称
CREG1 Rabbit Polyclonal Antibody
基因名称
CREG1 CREG UNQ727/PRO1409
蛋白名称
Protein CREG1 (Cellular repressor of E1A-stimulated genes 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O75629
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O75629/entry
Mouse Swissprot No.
O88668
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O88668
免疫原
Synthesized peptide derived from part region of human protein
特异性
CREG1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation. [provided by RefSeq, Jul 2008],
组织表达
Liver,Lymph,Placenta,
功能
function:May contribute to the transcriptional control of cell growth and differentiation. Antagonizes transcriptional activation and cellular transformation by the adenovirus E1A protein. The transcriptional control activity of cell growth requires interaction with IGF2R.,PTM:N-glycosylated.,similarity:Belongs to the CREG family.,subunit:Homodimer. Interacts with IGF2R; the interaction is dependent on glycosylation.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
