产品名称
RASM Rabbit Polyclonal Antibody
蛋白名称
Ras-related protein M-Ras (Ras-related protein R-Ras3)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O14807
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O14807/entry
Mouse Swissprot No.
O08989
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O08989
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P97538
免疫原
Synthesized peptide derived from part region of human protein
特异性
RASM Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
组织表达
Expression highly restricted to the brain and heart.
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side .
信号通路
MAPK_ERK_Growth;MAPK_G_Protein;Tight junction;Regulates Actin and Cytoskeleton;
功能
function:May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway.,induction:By interleukin-9, but not by IL-2 or IL-4.,similarity:Belongs to the small GTPase superfamily. Ras family.,subunit:Interacts with RGL3.,tissue specificity:Expression highly restricted to the brain and heart.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
