产品名称
SLIK5 Rabbit Polyclonal Antibody
基因名称
SLITRK5 KIAA0918 LRRC11
蛋白名称
SLIT and NTRK-like protein 5 (Leucine-rich repeat-containing protein 11)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O94991
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O94991/entry
Mouse Swissprot No.
Q810B7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q810B7
免疫原
Synthesized peptide derived from part region of human protein
特异性
SLIK5 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).[supplied by OMIM, Mar 2008],
组织表达
Expressed predominantly in the cerebral cortex of the brain but also at low levels in the spinal cord and medulla.
细胞定位
Membrane ; Single-pass type I membrane protein .
功能
function:Suppresses neurite outgrowth.,similarity:Belongs to the SLITRK family.,similarity:Contains 16 LRR (leucine-rich) repeats.,tissue specificity:Expressed predominantly in the cerebral cortex of the brain but also at low levels in the spinal cord and medulla.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
