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Periostin (Periostin) (7W9) Mouse Monoclonal antibody

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产品基本信息

产品货号
BD-PE3034
产品名称
Periostin (Periostin) (7W9) Mouse Monoclonal antibody
类别
常规抗体
基因名称
Periostin
推荐应用
WB
反应种属
Human,Mouse,Rat
存储缓冲液
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.
免疫原
Human recombinant protein fragment corresponding to amino acids 1-230 of human periostin (NP_006466) produced in E.coli.
稀释度
WB 1:500, IF 1:100
预测分子量
93.2kDa
运输及保存条件
-20°C/1 year
宿主
Mouse
同种型
IgM
背景介绍
Periostin is a disulfide linked 90 kDa, 811 amino acid protein originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta 1(TGF beta 1) and bone morphogenetic protein (BMP2). Periostin mRNA is expressed in the developing mouse embryonic and fetal heart, and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart. Abnormal expression of periostin is also linked to angiogenesis and metastatsis in epithelial tumors.
期货
现货
纯化
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Immunofluorescent staining of COS7 cells transfected by pCMV6-ENTRY POSTN using anti-POSTN mouse monoclonal antibody (Cat# BD-PE3034).

HeLa cells were transfected with human periostin cDNA and lysed. Cell lysates were separated by SDS-PAGE and immunoblotted with anti-POSTN mouse monoclonal antibody (Cat# BD-PE3034).

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