BD-PE3007

RNASEH2A (6Z16) Mouse Monoclonal antibody

常规抗体

Ribonuclease H2, subunit A

WB

Human,Mouse

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Full length human recombinant protein of human RNASEH2A (NP_006388) produced in E.coli.

WB 1:500-1:2000

33.4kDa

-20°C/1 year

Mouse

IgG1

The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009]

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)