产品名称
GNLY Rabbit Polyclonal Antibody
基因名称
GNLY LAG2 NKG5 TLA519
蛋白名称
Granulysin (Lymphokine LAG-2) (Protein NKG5) (T-cell activation protein 519)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P22749
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P22749/entry
免疫原
Synthesized peptide derived from part region of human protein
特异性
GNLY Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
组织表达
Expressed in natural killer and T-cells.
细胞定位
Secreted. Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation.
功能
function:Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.,induction:By T-cell growth factor and interleukin-2.,PTM:A 9 kDa form is produced by proteolytic processing of a 15 kDa protein.,similarity:Contains 1 saposin B-type domain.,subcellular location:Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation.,tissue specificity:Expressed in natural killer and T-cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
