BD-PE2925-PEG3 (10A1) Mouse Monoclonal antibody-现货抗体产品库武汉枢密脑科学技术有限公司

PEG3 (10A1) Mouse Monoclonal antibody

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产品基本信息

产品货号

BD-PE2925

产品名称

PEG3 (10A1) Mouse Monoclonal antibody

类别

常规抗体

基因名称

PEG3

推荐应用

反应种属

Human

存储缓冲液

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

免疫原

Human recombinant protein fragment corresponding to amino acids 1-364 of human PEG3 (NP_006201) produced in E.coli.

稀释度

WB 1:2000, IHC 1:150

预测分子量

180.6kDa

运输及保存条件

-20°C/1 year

宿主

Mouse

同种型

IgG1

背景介绍

In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2009]

期货

现货

纯化

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-PEG3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE2925)

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-PEG3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE2925)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PEG3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE2925)

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-PEG3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE2925)

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PEG3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PEG3(Cat# BD-PE2925). Positive lysates (100ug) and (20ug) can be purchased separately from OriGene.