产品名称
CXL14 Rabbit Polyclonal Antibody
基因名称
CXCL14 MIP2G NJAC SCYB14 PSEC0212 UNQ240/PRO273
蛋白名称
C-X-C motif chemokine 14 (Chemokine BRAK) (MIP-2G) (Small-inducible cytokine B14)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O95715
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O95715/entry
Mouse Swissprot No.
Q9WUQ5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9WUQ5
免疫原
Synthesized peptide derived from part region of human protein AA range: 1-50
特异性
CXL14 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
C-X-C motif chemokine ligand 14(CXCL14) Homo sapiens This antimicrobial gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. [provided by RefSeq, Sep 2014],
组织表达
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highly expressed in normal tissue without inflammatory stimuli and infrequently expressed in cancer cell lines. Weakly expressed in monocyte-derived dendritic cells. Not detected in lung or unstimulated peripheral blood lymphocytes.
信号通路
Cytokine-cytokine receptor interaction;Chemokine;
功能
function:Not chemotactive for T-cells, B-cells, monocytes, natural killer cells or ghranulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays.,online information:CXCL14 entry,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,tissue specificity:Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highly expressed in normal tissue without inflammatory stimuli and infrequently expressed in cancer cell lines.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
