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TRIM22 (18C3) Mouse Monoclonal antibody

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产品基本信息

产品货号
BD-PE2855
产品名称
TRIM22 (18C3) Mouse Monoclonal antibody
类别
常规抗体
基因名称
TRIM22
推荐应用
WB
反应种属
Human
存储缓冲液
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.
免疫原
Human recombinant protein fragment corresponding to amino acids 61-406 of human TRIM22(NP_006065) produced in E.coli.
稀释度
WB 1:500, IHC 1:150, IF 1:100
预测分子量
56.8kDa
运输及保存条件
-20°C/1 year
宿主
Mouse
同种型
IgG1
背景介绍
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
期货
现货
纯化
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-TRIM22 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE2855)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-TRIM22 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE2855)

Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-TRIM22 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE2855)

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-TRIM22 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE2855)

Anti-TRIM22 mouse monoclonal antibody (BD-PE2855) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TRIM22 .

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TRIM22 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TRIM22(Cat# BD-PE2855). Positive lysates (100ug) and (20ug) can be purchased separately from OriGene.

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