产品名称
DYN3 Rabbit Polyclonal Antibody
蛋白名称
Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9UQ16
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UQ16/entry
Mouse Swissprot No.
Q8BZ98
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BZ98
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q08877
免疫原
Synthesized peptide derived from part region of human protein
特异性
DYN3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
dynamin 3(DNM3) Homo sapiens This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton . Microtubule-associated. .
信号通路
Endocytosis;Fc gamma R-mediated phagocytosis;
功能
catalytic activity:GTP + H(2)O = GDP + phosphate.,function:Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis.,similarity:Belongs to the dynamin family.,similarity:Contains 1 GED domain.,similarity:Contains 1 PH domain.,subcellular location:Microtubule-associated.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
