产品名称
TXND2 Rabbit Polyclonal Antibody
蛋白名称
Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q86VQ3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q86VQ3/entry
Mouse Swissprot No.
Q6P902
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6P902
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q5XHX6
免疫原
Synthesized peptide derived from part region of human protein
特异性
TXND2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.,similarity:Contains 1 thioredoxin domain.,subcellular location:In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.,tissue specificity:Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids.,
组织表达
Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids.
细胞定位
Cytoplasm . In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.
功能
function:Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.,similarity:Contains 1 thioredoxin domain.,subcellular location:In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.,tissue specificity:Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
