产品名称
DYN3 Rabbit Polyclonal Antibody
蛋白名称
Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9UQ16
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UQ16/entry
Mouse Swissprot No.
Q8BZ98
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BZ98
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q08877
免疫原
Synthesized peptide derived from part region of human protein
特异性
DYN3 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
dynamin 3(DNM3) Homo sapiens This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton . Microtubule-associated. .
信号通路
Endocytosis;Fc gamma R-mediated phagocytosis;
功能
catalytic activity:GTP + H(2)O = GDP + phosphate.,function:Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis.,similarity:Belongs to the dynamin family.,similarity:Contains 1 GED domain.,similarity:Contains 1 PH domain.,subcellular location:Microtubule-associated.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
