产品名称
PP2BB Rabbit Polyclonal Antibody
基因名称
PPP3CB CALNA2 CALNB CNA2
蛋白名称
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calmodulin-dependent calcineurin A subunit beta isoform)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P16298
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P16298/entry
Mouse Swissprot No.
P48453
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P48453
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P20651
免疫原
Synthesized peptide derived from part region of human protein
特异性
PP2BB Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
alternative products:Additional isoforms seem to exist. Calcineurin A beta isoform consists of at least two isoenzymes that may result from alternative splicing events,catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,cofactor:Binds 1 Fe(3+) ion per subunit.,cofactor:Binds 1 zinc ion per subunit.,function:Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.,similarity:Belongs to the PPP phosphatase family.,similarity:Belongs to the PPP phosphatase family. PP-2B subfamily.,subunit:Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.,
组织表达
Teratocarcinoma,Testis,
信号通路
MAPK_ERK_Growth;MAPK_G_Protein;Calcium;Oocyte meiosis;Apoptosis_Inhibition;Apoptosis_Mitochondrial;Apoptosis_Overview;WNT;WNT-T CELLAxon guidance;VEGF;Natural killer cell mediated cytotoxicity;T_Cell_Receptor;B_Cell_Antigen;Long-term potentiation;Alzheime
功能
alternative products:Additional isoforms seem to exist. Calcineurin A beta isoform consists of at least two isoenzymes that may result from alternative splicing events,catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,cofactor:Binds 1 Fe(3+) ion per subunit.,cofactor:Binds 1 zinc ion per subunit.,function:Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.,similarity:Belongs to the PPP phosphatase family.,similarity:Belongs to the PPP phosphatase family. PP-2B subfamily.,subunit:Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
