产品名称
VASN Rabbit Polyclonal Antibody
基因名称
VASN SLITL2 UNQ314/PRO357/PRO1282
蛋白名称
Vasorin (Protein slit-like 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q6EMK4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6EMK4/entry
Mouse Swissprot No.
Q9CZT5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CZT5
免疫原
Synthesized peptide derived from part region of human protein
特异性
VASN Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:May act as an inhibitor of TGF-beta signaling.,PTM:N-glycosylated.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,subunit:Interacts with TGFB1, TGFB2 and TGFB3.,tissue specificity:Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells.,
组织表达
Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells.
细胞定位
Membrane ; Single-pass type I membrane protein . Secreted .
功能
function:May act as an inhibitor of TGF-beta signaling.,PTM:N-glycosylated.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,subunit:Interacts with TGFB1, TGFB2 and TGFB3.,tissue specificity:Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
