BD-PN2039

SCRB2 Rabbit Polyclonal Antibody

常规抗体

SCARB2 CD36L2 LIMPII

Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) (CD antigen CD36)

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

950

Q14108

https://www.uniprot.org/uniprotkb/Q14108/entry

O35114

http://www.uniprot.org/uniprot/O35114

P27615

http://www.uniprot.org/uniprot/O54941P27615

Synthesized peptide derived from part region of human protein

SCRB2 Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000 ELISA 1:5000-20000

52kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encod

Cerebellum,Eye,Liver,Mammary cancer,

Lysosome membrane ; Multi-pass membrane protein .

Lysosome;

disease:Defects in SCARB2 are the cause of action myoclonus-renal failure syndrome (AMRF) [MIM:254900]; also known as myoclonus-nephropathy syndrome. AMRF is an autosomal recessive progressive myoclonic epilepsy associated with renal failure. Myoclonus is a brief, involuntary twitching of a muscle or a group of muscles. Cognitive function is preserved.,function:May act as a lysosomal receptor.,mass spectrometry: PubMed:11840567,similarity:Belongs to the CD36 family.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.