产品名称
REL1 Rabbit Polyclonal Antibody
蛋白名称
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P04808
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P04808/entry
Mouse Swissprot No.
P47932
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P47932
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P01347
免疫原
Synthesized peptide derived from part region of human protein
特异性
REL1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
relaxin 1(RLN1) Homo sapiens Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. [provided by RefSeq, Jan 2013],
组织表达
Prostate. Not expressed in placenta, decidua or ovary.
功能
function:Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.,similarity:Belongs to the insulin family.,subunit:Heterodimer of a B chain and an A chain linked by two disulfide bonds.,tissue specificity:Prostate. Not expressed in placenta, decidua or ovary.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
