BD-PE2329

STX1A (5C6) Mouse Monoclonal antibody

常规抗体

Syntaxin 1a

WB

Human,Rat,Mouse

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Full length human recombinant protein of human STX1A (NP_004594) produced in E.coli.

WB 1:500, IF 1:100

-20°C/1 year

Mouse

IgG2a

This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)