产品名称
SORC1 Rabbit Polyclonal Antibody
蛋白名称
VPS10 domain-containing receptor SorCS1 (hSorCS)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8WY21
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8WY21/entry
Mouse Swissprot No.
Q9JLC4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9JLC4
免疫原
Synthesized peptide derived from part region of human protein
特异性
SORC1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
组织表达
Detected in fetal and infant brain and in fetal retina.
细胞定位
Membrane; Single-pass type I membrane protein.
功能
similarity:Contains 1 PKD domain.,similarity:Contains 5 BNR repeats.,tissue specificity:Detected in fetal and infant brain and in fetal retina.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.