产品名称
PGRP4 Rabbit Polyclonal Antibody
基因名称
PGLYRP4 PGRPIB SBBI67
蛋白名称
Peptidoglycan recognition protein 4 (Peptidoglycan recognition protein I-beta) (PGLYRPIbeta) (PGRP-I-beta) (Peptidoglycan recognition protein intermediate beta)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q96LB8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96LB8/entry
Mouse Swissprot No.
Q0VB07
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q0VB07
免疫原
Synthesized peptide derived from part region of human protein AA range: 81-130
特异性
PGRP4 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Summary: This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014],
组织表达
Detected in skin epidermis, eccrine sweat glands and ducts, mucous cells in the submandibular salivary gland, mucous cells in the throat, ciliary body epithelial cells of the eye, small intestine, colon, stomach and in mature epithelial cells of the tongue (at protein level). High expression in skin and esophagus. Expressed also to a much lesser extent in the tonsils and thymus.
功能
function:Binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May play a role in innate immunity.,similarity:Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.,tissue specificity:High expression in the esophagus. Expressed also to a much lesser extent in the tonsils and thymus.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
