BD-PE2102-BCL10 (4M18) Mouse Monoclonal antibody-现货抗体产品库武汉枢密脑科学技术有限公司

BCL10 (4M18) Mouse Monoclonal antibody

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产品基本信息

产品货号

BD-PE2102

产品名称

BCL10 (4M18) Mouse Monoclonal antibody

类别

常规抗体

基因名称

BCL10

推荐应用

反应种属

Human,Mouse,Rat

存储缓冲液

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

免疫原

Full length human recombinant protein of human BCL10 (NP_003912) produced in HEK293T cell.

稀释度

WB 1:2000, IHC 1:50, IF 1:100, FCM 1:100

预测分子量

26.1kDa

运输及保存条件

-20°C/1 year

宿主

Mouse

同种型

IgG1

背景介绍

This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.

期货

现货

纯化

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-BCL10 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, BD-PE2102, Dilution 1:50)

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BCL10 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL10. Positive lysates (100ug) and (20ug) can be purchased separately from OriGene.

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-BCL10 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, BD-PE2102, Dilution 1:50)

Flow cytometric Analysis of Jurkat cells, using anti-BCL10 antibody (BD-PE2102), (Red), compared to a nonspecific negative control antibody , (Blue).

Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-BCL10 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, BD-PE2102, Dilution 1:50)

Anti-BCL10 mouse monoclonal antibody (BD-PE2102) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BCL10.