产品名称
LAP2A Rabbit Polyclonal Antibody
蛋白名称
Lamina-associated polypeptide 2, isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Cleaved into: Thymopoietin (TP) (Splenin); Thymopentin (TP5)]
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P42166
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P42166/entry
Mouse Swissprot No.
Q61033
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q61033
免疫原
Synthesized peptide derived from part region of human protein
特异性
LAP2A Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Thymopoietin encoded by TMPO resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in this gene are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
组织表达
Expressed in many tissues. Most abundant in adult thymus and fetal liver.
细胞定位
Nucleus. Chromosome. Expressed diffusely throughout the nucleus.
功能
regulation of transcription,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
