产品名称
FLRT3 Rabbit Polyclonal Antibody
基因名称
FLRT3 KIAA1469 UNQ856/PRO1865
蛋白名称
Leucine-rich repeat transmembrane protein FLRT3 (Fibronectin-like domain-containing leucine-rich transmembrane protein 3)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NZU0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NZU0/entry
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941B1H234
免疫原
Synthesized peptide derived from part region of human protein
特异性
FLRT3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
fibronectin leucine rich transmembrane protein 3(FLRT3) Homo sapiens This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRTs may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. This gene is expressed in many tissues. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2010],
组织表达
Expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart.
细胞定位
Cell membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane . Cell junction, focal adhesion . Secreted . Cell projection, axon . Cell projection, growth cone membrane . Detected on dendritic punctae that colocalize in part with glutamaergic synapses, but not with GABAergic synapses. Proteolytic cleavage in the juxtamembrane region gives rise to a shedded ectodomain. .
功能
function:May have a function in cell adhesion and/or receptor signaling.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 10 LRR (leucine-rich) repeats.,tissue specificity:Expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
