产品名称
FLRT3 Rabbit Polyclonal Antibody
基因名称
FLRT3 KIAA1469 UNQ856/PRO1865
蛋白名称
Leucine-rich repeat transmembrane protein FLRT3 (Fibronectin-like domain-containing leucine-rich transmembrane protein 3)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NZU0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NZU0/entry
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941B1H234
免疫原
Synthesized peptide derived from part region of human protein
特异性
FLRT3 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
fibronectin leucine rich transmembrane protein 3(FLRT3) Homo sapiens This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRTs may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. This gene is expressed in many tissues. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2010],
组织表达
Expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart.
细胞定位
Cell membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane . Cell junction, focal adhesion . Secreted . Cell projection, axon . Cell projection, growth cone membrane . Detected on dendritic punctae that colocalize in part with glutamaergic synapses, but not with GABAergic synapses. Proteolytic cleavage in the juxtamembrane region gives rise to a shedded ectodomain. .
功能
function:May have a function in cell adhesion and/or receptor signaling.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 10 LRR (leucine-rich) repeats.,tissue specificity:Expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
