BD-PE1611-PIK3C2B (1J11) Mouse Monoclonal antibody-现货抗体产品库武汉枢密脑科学技术有限公司

PIK3C2B (1J11) Mouse Monoclonal antibody

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产品基本信息

产品货号

BD-PE1611

产品名称

PIK3C2B (1J11) Mouse Monoclonal antibody

类别

常规抗体

基因名称

PIK3C2B

推荐应用

反应种属

Human,Mouse,Rat

存储缓冲液

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

免疫原

Full length human recombinant protein of human PIK3C2B(NP_002637) produced in HEK293T cell.

稀释度

WB 1:1000, IHC 1:150

运输及保存条件

-20°C/1 year

宿主

Mouse

同种型

IgG1

背景介绍

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner. [provided by RefSeq, Jul 2008]

期货

现货

纯化

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-PIK3C2B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE1611)

Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-PIK3C2B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE1611)

Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-PIK3C2B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE1611)

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-PIK3C2B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE1611)

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-PIK3C2B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE1611)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PIK3C2B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE1611)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PIK3C2B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE1611)

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PIK3C2B (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PIK3C2B(Cat# BD-PE1611). Positive lysates (100ug) and (20ug) can be purchased separately from OriGene.