产品名称
DSCL1 Rabbit Polyclonal Antibody
基因名称
DSCAML1 DSCAM2 KIAA1132
蛋白名称
Down syndrome cell adhesion molecule-like protein 1 (Down syndrome cell adhesion molecule 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8TD84
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8TD84/entry
Mouse Swissprot No.
Q4VA61
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q4VA61
免疫原
Synthesized peptide derived from part region of human protein
特异性
DSCL1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the Ig superfamily of cell adhesion molecules and is involved in neuronal differentiation. The encoded membrane-bound protein localizes to the cell surface, where it forms aggregates that repel neuronal processes of the same cell type. [provided by RefSeq, Sep 2016],
组织表达
Detected in heart, liver, pancreas, skeletal muscle, kidney and in brain, in particular in the amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra, thalamus and subthalamus.
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse .
功能
function:Cell adhesion molecule that can mediate cation-independent homophilic binding activity. Could be involved in nervous system development.,similarity:Contains 10 Ig-like C2-type (immunoglobulin-like) domains.,similarity:Contains 6 fibronectin type-III domains.,tissue specificity:Detected in heart, liver, pancreas, skeletal muscle, kidney and in brain, in particular in the amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra, thalamus and subthalamus.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
