BD-PE1594

PDE4B (7F6) Mouse Monoclonal antibody

常规抗体

PDE4

WB

Human,Mouse,Rat

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Full length human recombinant protein of human PDE4B(NP_002591) produced in HEK293T cell.

WB 1:500~2000, FCM 1:100

83.2kDa

-20°C/1 year

Mouse

IgG1

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)