产品名称
LAMB4 Rabbit Polyclonal Antibody
蛋白名称
Laminin subunit beta-4 (Laminin beta-1-related protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
A4D0S4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/A4D0S4/entry
免疫原
Synthesized peptide derived from part region of human protein
特异性
LAMB4 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
domain:Domains VI and IV are globular.,domain:The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.,function:Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.,similarity:Contains 1 laminin IV type B domain.,similarity:Contains 1 laminin N-terminal domain.,similarity:Contains 13 laminin EGF-like domains.,subunit:Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end.,
细胞定位
Secreted, extracellular space, extracellular matrix, basement membrane.
信号通路
Focal adhesion;ECM-receptor interaction;Pathways in cancer;Small cell lung cancer;
功能
domain:Domains VI and IV are globular.,domain:The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.,function:Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.,similarity:Contains 1 laminin IV type B domain.,similarity:Contains 1 laminin N-terminal domain.,similarity:Contains 13 laminin EGF-like domains.,subunit:Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.