BD-PE1578-PARN (8W19) Mouse Monoclonal antibody-现货抗体产品库武汉枢密脑科学技术有限公司

PARN (8W19) Mouse Monoclonal antibody

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产品基本信息

产品货号

BD-PE1578

产品名称

PARN (8W19) Mouse Monoclonal antibody

类别

常规抗体

基因名称

PARN

推荐应用

反应种属

Human,Mouse,Rat

存储缓冲液

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

免疫原

Human recombinant protein fragment corresponding to amino acids 1-266 of human PARN (NP_002573) produced in E.coli.

特异性

Validated through 10k CHIP testing，using a High-Density Protein Microarray that was spotted with ~17,000 various over-expressed proteins to test for antibody specificity.

稀释度

WB 1:2000, IHC 1:100~200

运输及保存条件

-20°C/1 year

宿主

Mouse

同种型

IgG2a

背景介绍

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

期货

现货

纯化

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-PARN mouse monoclonal antibody (BD-PE1578). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification.

Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-PARN mouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-PARNmouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-PARN mouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)

Immunohistochemical staining of paraffin-embedded Human lung tissue using anti-PARN mouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PARN mouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)

Immunohistochemical staining of paraffin-embedded Human thyroid tissue using anti-PARN mouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)

Immunohistochemical staining of paraffin-embedded Human tonsil using anti-PARNmouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-PARN mouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)

Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-PARN mouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-PARN mouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)

Western blot of human tissue lysates (15ug) from 10 different tissues (1: Testis, 2: Omentum, 3: Uterus, 4: Breast, 5: Brain, 6: Liver, 7: Ovary, 8: Thyroid, 9: Colon, 10: Spleen). Diluation: 1:500.

Immunohistochemical staining of paraffin-embedded Human bladder tissue using anti-PARN mouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-PARNmouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-PARN mouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)

Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-PARN mouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)

Immunohistochemical staining of paraffin-embedded Human lymph node tissue using anti-PARN mouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PARN mouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)

Western blot analysis of RPMI8226 cell lysate (35ug) by using anti-PARN monoclonal antibody.

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-PARN mouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PARN mouse monoclonal antibody. (BD-PE1578; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120°C for 3min)