产品名称
XPP1 Rabbit Polyclonal Antibody
基因名称
XPNPEP1 XPNPEPL XPNPEPL1
蛋白名称
Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NQW7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NQW7/entry
Mouse Swissprot No.
Q6P1B1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6P1B1
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941O54975
免疫原
Synthesized peptide derived from part region of human protein
特异性
XPP1 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009],
组织表达
Expressed in all tissues tested, including pancreas, heart, muscle, kidney, liver, lung and brain. Highest levels in pancreas.
功能
catalytic activity:Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.,cofactor:Manganese.,enzyme regulation:Inhibited by apstatin and the metal ion chelators EDTA and 1,10-phenanthroline. Partially inhibited by dithiothreitol. Not inhibited by enalaprilat or amastatin.,similarity:Belongs to the peptidase M24B family.,subunit:Homodimer.,tissue specificity:Expressed in all tissues tested, including pancreas, heart, muscle, kidney, liver, lung and brain. Highest levels in pancreas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
