产品名称
UTF1 Rabbit Polyclonal Antibody
蛋白名称
Undifferentiated embryonic cell transcription factor 1
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q5T230
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q5T230/entry
Mouse Swissprot No.
Q6J1H4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6J1H4
免疫原
Synthesized peptide derived from part region of human protein
特异性
UTF1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a leucine zipper-containing transcriptional coactivator that may link the upstream activator ATF2 with the basal transcription complex. The encoded protein is closely associated with chromatin and is required for the proper differentiation of embryonic carcinoma and embryonic stem cells. Found nearly exclusively in pluripotent cells, this protein can also serve as a transcriptional repressor. [provided by RefSeq, Nov 2015],
功能
domain:The leucine-zipper domain is required for coactivation activity. When this domain is deleted, the protein is able to stimulate transcription from a number of gene promoters.,function:Acts as a transcriptional coactivator of ATF2.,PTM:Phosphorylated.,subunit:Binds to the N-terminal region of ATF2. Associates with the TFIID complex through interaction with TBP.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
