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KLRB1 (12O9) Mouse Monoclonal antibody

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产品基本信息

产品货号
BD-PE1416
产品名称
KLRB1 (12O9) Mouse Monoclonal antibody
类别
常规抗体
基因名称
CD161
推荐应用
WB
反应种属
Human
存储缓冲液
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.
免疫原
Human recombinant protein fragment corresponding to amino acids 67-225 of human KLRB1(NP_002249) produced in E.coli.
稀释度
WB 1:500, IHC 1:500
预测分子量
25.2kDa
运输及保存条件
-20°C/1 year
宿主
Mouse
同种型
IgG1
背景介绍
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq, Jul 2008]
期货
现货
纯化
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Immunohistochemical staining of paraffin-embedded Human spleen tissue within the normal limits using anti-KLRB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA (1:500)

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY KLRB1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-KLRB1 (Cat# BD-PE1416)(1:500). Positive lysates (100ug) and (20ug) can be purchased separately from OriGene.

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