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H2AX (16R4) Rabbit Monoclonal antibody

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产品基本信息

产品货号
RM1377
产品名称
H2AX (16R4) Rabbit Monoclonal antibody
类别
常规抗体
基因名称
Histone H2A.X
推荐应用
WB
反应种属
Human,Mouse
存储缓冲液
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.
免疫原
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human H2AX (NP_002096). The exact sequence is proprietary.
稀释度
WB 1:500-1:5000
预测分子量
15.1kDa
运输及保存条件
-20°C/1 year
宿主
Rabbit
同种型
IgG
背景介绍
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015]
期货
现货
纯化
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Western blot analysis of extracts (50ug per lane) from 2 cell lines lysates by using anti-H2AX monoclonal antibody(RM1377, 1:500)

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