产品名称
SOX3 Rabbit Polyclonal Antibody
蛋白名称
Transcription factor SOX-3
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P41225
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P41225/entry
Mouse Swissprot No.
P53784
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P53784
免疫原
Synthesized peptide derived from part region of human protein
特异性
SOX3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
SRY-box 3(SOX3) Homo sapiens This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency. [provided by RefSeq, Jul 2008],
功能
caution:Was originally (PubMed:1614875) termed SOX-9.,disease:Defects in SOX3 are a cause of panhypopituitarism X-linked (PHPX) [MIM:312000]. Affected individuals have absent infundibulum, anterior pituitary hypoplasia, and ectopic posterior pituitary.,disease:Defects in SOX3 are the cause of mental retardation X-linked with isolated growth hormone deficiency (MRXGH) [MIM:300123].,similarity:Contains 1 HMG box DNA-binding domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
