BD-PE1342-FMR1 (FMRP ) (6Y6) Mouse Monoclonal antibody-现货抗体产品库武汉枢密脑科学技术有限公司

FMR1 (FMRP ) (6Y6) Mouse Monoclonal antibody

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产品基本信息

产品货号

BD-PE1342

产品名称

FMR1 (FMRP ) (6Y6) Mouse Monoclonal antibody

类别

常规抗体

基因名称

FMRP

推荐应用

反应种属

Human,Dog,Rat,Monkey,Mouse

存储缓冲液

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

免疫原

Human recombinant protein fragment corresponding to amino acids 36-279 of human FMR1(NP_002015) produced in E.coli.

稀释度

WB 1:500~2000, IHC 1:150, IF 1:100, FCM 1:100

预测分子量

71kDa

运输及保存条件

-20°C/1 year

宿主

Mouse

同种型

IgG1

背景介绍

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]

期货

现货

纯化

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Flow cytometric Analysis of Jurkat cells, using anti-FMR1 antibody (BD-PE1342), (Red), compared to a nonspecific negative control antibody, (Blue).

Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, BD-PE1342)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, BD-PE1342)

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-FMR1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, BD-PE1342)

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, BD-PE1342)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, BD-PE1342)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, BD-PE1342)

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, BD-PE1342)

Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, BD-PE1342)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, BD-PE1342)

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, BD-PE1342)

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, BD-PE1342)

Anti-FMR1 mouse monoclonal antibody (BD-PE1342) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FMR1 .

Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, BD-PE1342)

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FMR1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FMR1 (Cat# BD-PE1342). Positive lysates (100ug) and (20ug) can be purchased separately from OriGene.