产品名称
PSD4 Rabbit Polyclonal Antibody
蛋白名称
PH and SEC7 domain-containing protein 4 (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B) (Exchange factor for ARF6 B) (Pleckstrin homology and SEC7 domain-containing protein 4) (Telomeric of interleukin-1 cluster protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8NDX1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8NDX1/entry
Mouse Swissprot No.
Q8BLR5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BLR5
免疫原
Synthesized peptide derived from part region of human protein
特异性
PSD4 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Guanine nucleotide exchange factor for ARF6-like protein. Involved in membrane recycling.,similarity:Contains 1 PH domain.,similarity:Contains 1 SEC7 domain.,subcellular location:Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures.,tissue specificity:Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.,
组织表达
Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.
细胞定位
Cell membrane . Cell projection, ruffle membrane . In interphase associated with the plasma membrane, in particular with membrane ruffling regions (PubMed:23603394). Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures (PubMed:12082148). Recruited to membranes via phosphatidylinositol phosphate-binding (Probable). .
功能
function:Guanine nucleotide exchange factor for ARF6-like protein. Involved in membrane recycling.,similarity:Contains 1 PH domain.,similarity:Contains 1 SEC7 domain.,subcellular location:Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures.,tissue specificity:Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
