BD-PE1299

HBEGF (16X3) Mouse Monoclonal antibody

常规抗体

HBEGF

WB

Human

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Human recombinant protein fragment corresponding to amino acids 20-208 of human HBEGF (NP_001936) produced in E.coli.

WB 1:2000

22.9kDa

-20°C/1 year

Mouse

IgG1

Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor. [UniProtKB/Swiss-Prot Function]

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)