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Desmin (1V12) Mouse Monoclonal antibody

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产品基本信息

产品货号
BD-PE1292
产品名称
Desmin (1V12) Mouse Monoclonal antibody
类别
常规抗体
基因名称
DES
推荐应用
WB
反应种属
Human,Mouse,Rat
存储缓冲液
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.
免疫原
Full length human recombiant protein of human DES(NP_001918) produced in E.coli.
稀释度
IHC 1:200
预测分子量
53.4kDa
运输及保存条件
-20°C/1 year
宿主
Mouse
同种型
IgG1
背景介绍
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008]
期货
现货
纯化
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-DES mouse monoclonal antibody. (BD-PE1292, heat-induced epitope retrieval by 1mM EDTA in 10mM Tris, pH8.0, 120°C for 3min)

Immunofluorescent staining of HeLa cells using anti-DES mouse monoclonal antibody (BD-PE1292, green, 1:50). Actin filaments were labeled with Alexa Fluor® 594 Phalloidin (red), and nuclear with DAPI (blue). Scale bar, 20µm.

Western blot of human tissue lysates (15ug) from colon. Diluation: 1:500.

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-DES mouse monoclonal antibody. (BD-PE1292, heat-induced epitope retrieval by 1mM EDTA in 10mM Tris, pH8.0, 120°C for 3min)

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