BD-PE1280

Beta-catenin (10U7) Mouse Monoclonal antibody

常规抗体

CTNNB1

WB

Human,Mouse,Rat

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Recombinant protein expressed in E.coli corresponding to amino acids 531-781 of human beta-catenin

WB 1:1000

85.3kDa

-20°C/1 year

Mouse

IgG1

Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the 'contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)