BD-PE1231-CDH3 (P cadherin) (19L16) Mouse Monoclonal antibody-现货抗体产品库武汉枢密脑科学技术有限公司

CDH3 (P cadherin) (19L16) Mouse Monoclonal antibody

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产品基本信息

产品货号

BD-PE1231

产品名称

CDH3 (P cadherin) (19L16) Mouse Monoclonal antibody

类别

常规抗体

基因名称

P cadherin

推荐应用

反应种属

Human

存储缓冲液

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

免疫原

Full length human recombinant protein of human CDH3(NP_001784) produced in HEK293T cell.

稀释度

WB 1:4000, IHC 1:150, IF 1:100

预测分子量

88.8kDa

运输及保存条件

-20°C/1 year

宿主

Mouse

同种型

IgG2a

背景介绍

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. [provided by RefSeq, Jul 2008]

期货

现货

纯化

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-CDH3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE1231)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-CDH3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE1231)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-CDH3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE1231)

Immunofluorescent staining of HeLa cells using anti-CDH3 mouse monoclonal antibody (BD-PE1231).

Anti-CDH3 mouse monoclonal antibody (BD-PE1231) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CDH3 .

Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-CDH3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE1231)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CDH3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE1231)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-CDH3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE1231)

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDH3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDH3 (Cat# BD-PE1231). Positive lysates (100ug) and (20ug) can be purchased separately from OriGene.