BD-PE1191-CD1C (18P9) Mouse Monoclonal antibody-现货抗体产品库武汉枢密脑科学技术有限公司

CD1C (18P9) Mouse Monoclonal antibody

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产品基本信息

产品货号

BD-PE1191

产品名称

CD1C (18P9) Mouse Monoclonal antibody

类别

常规抗体

基因名称

CD1C

推荐应用

反应种属

Human

存储缓冲液

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

免疫原

Full length human recombinant protein of human CD1C(NP_001756) produced in HEK293T cell.

特异性

Validated through 10k CHIP testing，using a High-Density Protein Microarray that was spotted with ~17,000 various over-expressed proteins to test for antibody specificity.

稀释度

IHC 1:100

预测分子量

35.7kDa

运输及保存条件

-20°C/1 year

宿主

Mouse

同种型

IgG1

背景介绍

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul

期货

现货

纯化

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-CD1C mouse monoclonal antibody (BD-PE1191). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification.

Immunohistochemical staining of paraffin-embedded human tonsil with mouse anti-CD1c 1:200 dilution of 1mg/mL using HIER citrate pressure chamber. Shown here is a composit of 10x and 20x Imaging of tonsil with expression cytoplasmic and membraneous staining pattern.

Western Blot analysis of MOLT-4 cell lysate (35ug) by using anti-CD1C monoclonal antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-CD1C mouse monoclonal antibody. (BD-PE1191; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min)