产品名称
ERK5 (6D10) Mouse Monoclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.79% New type preservative N.
Human Swissprot No.
Q13164
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q13164 /entry
免疫原
Synthesized peptide derived from human ERK5
特异性
This antibody detects endogenous levels of ERK5 at Human, Mouse,Rat
稀释度
IHC-p1:50-200 ,WB 1:1000-2000
背景介绍
ERK5, Mitogen-activated protein kinase 7 also known as MAP kinase 7 is an enzyme that in humans is encoded by the MAPK7 gene. MAPK7 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.
组织表达
Expressed in many adult tissues. Abundant in heart, placenta, lung, kidney and skeletal muscle. Not detectable in liver.
细胞定位
Cytoplasm. Nucleus. Nucleus, PML body. Translocates to the nucleus upon activation.
纯化
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
