BD-PE1086

GSTA4 (10F7) Mouse Monoclonal antibody

常规抗体

GSTA4

WB

Human

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Full length human recombinant protein of human GSTA4 (NP_001503) produced in HEK293T cell.

WB: 1:500-1:2000, FCM: 1:100, IHC: 1:50-1:150

25.5kDa

-20°C/1 year

Mouse

IgG1

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis.

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)