产品名称
TBB1 Rabbit Polyclonal Antibody
蛋白名称
Tubulin beta-1 chain
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9H4B7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H4B7/entry
Mouse Swissprot No.
A2AQ07
Mouse Swissprot Link
http://www.uniprot.org/uniprot/A2AQ07
免疫原
Synthesized peptide derived from part region of human protein AA range: 257-307
特异性
TBB1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010],
组织表达
Hematopoietic cell-specific. Major isotype in leukocytes, where it represents 50% of all beta-tubulins.
细胞定位
Cytoplasm, cytoskeleton .
信号通路
Gap junction;Pathogenic Escherichia coli infection;
功能
function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
