产品名称
APOA2 Rabbit Polyclonal Antibody
蛋白名称
Apolipoprotein A-II (Apo-AII) (ApoA-II) (Apolipoprotein A2) [Cleaved into: Truncated apolipoprotein A-II (Apolipoprotein A-II(1-76))]
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P02652
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P02652/entry
Mouse Swissprot No.
P09813
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P09813
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P04638
免疫原
Synthesized peptide derived from part region of human protein AA range: 1-50
特异性
APOA2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008],
组织表达
Plasma; synthesized in the liver and intestine.
功能
function:May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.,mass spectrometry: PubMed:12562854,mass spectrometry:Cysteinylated ApoA-II PubMed:12562854,mass spectrometry:Heterodimer with apolipoprotein A-II(1-76) PubMed:12562854,mass spectrometry:Homodimer PubMed:12562854,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the apolipoprotein A2 family.,subunit:Homodimer; disulfide-linked. Also forms a disulfide-linked heterodimer with APOD. Interacts with HCV core protein. Interacts with APOA1BP.,tissue specificity:Plasma; synthesized in the liver and intestine.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
