BD-PE1000

IL15RA (1B2) Mouse Monoclonal antibody

常规抗体

IL15RA

WB

Human

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Human recombinant protein fragment corresponding to amino acids 31-267 of human IL15RA (NP_001230468) produced in E.coli.

WB 1:500

28.22kDa

-20°C/1 year

Mouse

IgG1

This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Apr 2010]

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)