产品名称
Gamma Tubulin(6C12)Mouse Monoclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7283
Human Swissprot No.
P23258
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P23258/entry
Mouse Swissprot No.
P83887
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P83887
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P83888
免疫原
Synthetic Peptide of Gamma Tubulin
特异性
Gamma Tubulin protein detects endogenous levels of TUBG1
稀释度
WB 1:1000-2000, IHC 1:100-200. IF 1:50-200
背景介绍
This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq, Jan 2009],
组织表达
Mammary cancer,Skin,
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Localizes to mitotic spindle microtubules. .
功能
function:Tubulin is the major constituent of microtubules. Gamma tubulin is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.,mass spectrometry: PubMed:11840567,similarity:Belongs to the tubulin family.,subunit:Interacts with GCP2 and GCP3. Interacts with B9D2.,
纯化
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
